The Center for Experimental Bioinformatics (CEBI), Department of Biochemistry and Molecular Biology at the University of Southern Denmark in Odense (website) applies modern methods of mass spectrometry and "proteomics" to the functional analysis of genes. The group has 25 members divided equally between analytical and biological specialties. We have a full range of techniques and state-of-the-art equipment both in molecular/cell biology and mass spectrometry/proteomics. Current projects are in stem cell biology in close collaboration with ‘The Danish Centre for Stem Cell Research’ based in Odense. Analytical topics include development of large-scale methods for protein identification, methods for generic isolation of multi-protein complexes, large-scale identification of protein modifications, searching of mass spectrometric data in sequence databases including genomic databases, use of mass spectrometry for the large scale analysis of protein function.

The Center for Experimental Bioinformatics' contribution to the Osteocord project is through characterisation using mass spectrometry based proteomics. Identification of markers and proteins differentially expressed by CB-MSCs and to determine specific and/or novel signalling factors important for CB-MSC differentiation. We will use quantitative proteomics methodology to ensure that CB-MSC specific proteins are identified through comparative analysis with BM-MSCs and ES cells. Identified proteins will be subjected to in depth bioinformatic analysis in relation to data obtained from genomic experiments by Partner 1.

Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, DENMARK

Professor Jens Andersen e-mail	Lars Kristensen e-mail

Click on the links to access the other Partners:

1. University of York, UK
2. University Hospital of Odense, Denmark
3. University of Southern Denmark
4. Fraunhofer Institute for Biomedical Engineering
5. University of Nottingham, UK
6. Institute of Transfusion Medicine and Immunology, Mannheim, Germany
7. Angel Biotechnology, Edinburgh, Scotland
8. EC Bio, Oeiras, Portugal
9. Regentec, Nottingham, UK