YCR P53 Research Unit
Department of Biology
University of York
YORK YO10 5DD, UK.
Tel (within UK):
(01904) 328620
Fax: (01904) 328622
Tel (outside UK):
+44-1904-328620
Fax: +44-1904-328622
E-mail: ajm24@york.ac.uk
Independent Investigator and Association for International Cancer
Research (AICR) Research Fellow
Wellcome Trust Centre for Gene Regulation and Expression
Dimitris Xirodimas was educated in Athens, Greece, before moving to Scotland in 1991 for his undergraduate studies at the University of Dundee. After graduation with a 1st class Honours Biochemistry degree in 1995, he joined Prof. Sir David Lane’s laboratory as a PhD student and then as post-doctoral research assistant. His studies were focussed on pathways and mechanisms that control the stability and function of the p53 tumour suppressor protein. In particular, his main interest was on the role of ubiquitin and ubiquitin-like molecules such as SUMO and NEDD8 in controlling p53 function. In 2004 he moved to the University of St-Andrews in Prof. Ronald Hay’s laboratory, as a post-doctoral research fellow to establish proteomic approaches for the identification of novel targets for the ubiquitin-like molecule NEDD8. In 2005, Dimitris established his own research team in the Wellcome Trust Centre for Gene Regulation and Expression at the University of Dundee through a Career Development Research Fellowship from the Association of International Cancer Research. His current research interest is on the role of the ubiquitin-like molecule NEDD8 in transcriptional regulation and cell growth.
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