Diagnoses relating to threats: particularly different anxiety disorders, and post-traumatic stress disorder
The cognitive neuroscience of how we process threats, including results from brain imaging and cognitive psychology
How differences in threat-processing might lead to anxiety disorders (such as phobias or generalized anxiety disorder)
How traumatic events might change how we experience threats
How understanding the above factors can inform intervention and clinical practice
The existence of threatening situations, stimuli or events is unfortunately a fact of life. Differences in how we process threats (and, indeed, in our thresholds for processing something as a threat) may result in anxiety disorders, which are globally some of the most common and debilitating mental illnesses. Relatedly, traumatic events may also change how we process threats.
The aim of this module is to allow students to understand how threats are processed, both cognitively and neurobiologically, and how threat processing may go awry. A subsidiary aim is to consider how this might change after traumatic experiences. At the end of the module, we will discuss how this knowledge can be applied to treatments for both anxiety disorders and post-traumatic stress disorder, and the potential for future interventions to be guided by cognitive neuroscience.
This module will be relevant to all students interested in understanding anxiety or PTSD from a cognitive neuroscience perspective, and to all those interested in further clinical work or research in anxiety or PTSD.
Module learning outcomes
Identify the similarities and differences between adaptive and maladaptive anxiety, and summarise evolutionary theories of anxiety’s adaptive role
Critically evaluate research showing how threat is processed in the brain, and relate these findings to clinical conditions such as phobia and generalised anxiety disorder
Synthesise evidence indicating how threat processing may be affected by traumatic experiences
Identify brain areas and/or circuits that may be altered after childhood maltreatment or trauma, paediatric PTSD, and adult PTSD
Clearly describe relevant constructs and their relationships: anxiety, fear, trauma, threat processing, PTSD, intolerance of uncertainty, catastrophizing
Critically discuss and suggest how cognitive neuroscience could be used to guide treatment development, and other clinical applications of cognitive neuroscience
Module content
Threat, and adaptive and maladaptive anxiety
Anxiety disorders and PTSD: similarities and differences
Brain areas involved in threat processing across species
A circuit-level approach to threat processing
Anxiety disorders and the neurobiology of threat processing
Traumatic experiences and the neurobiology of threat processing
Clinical psychology constructs: intolerance of uncertainty, catastrophizing
Treatments for anxiety and PTSD
Mechanisms of treatment
Future-focused session: how do we improve the situation?
Indicative assessment
Task
% of module mark
Essay/coursework
100
Special assessment rules
None
Indicative reassessment
Task
% of module mark
Essay/coursework
100
Module feedback
Marks will be released through e:vision.
Indicative reading
Robinson, O. J., Pike, A. C., Cornwell, B., & Grillon, C. (2019). The translational neural circuitry of anxiety. Journal of Neurology, Neurosurgery & Psychiatry, 90(12), 1353-1360.
Bentz, & Schiller, D. (2015). Threat processing: models and mechanisms. Wiley Interdisciplinary Reviews. Cognitive Science, 6(5), 427–439. https://doi.org/10.1002/wcs.1353
McCrory, E. J., Gerin, M. I., & Viding, E. (2017). Annual research review: childhood maltreatment, latent vulnerability and the shift to preventative psychiatry–the contribution of functional brain imaging. Journal of child psychology and psychiatry, 58(4), 338-357.
Robinson, Vytal, K., Cornwell, B. R., & Grillon, C. (2013). The impact of anxiety upon cognition: perspectives from human threat of shock studies. Frontiers in Human Neuroscience, 7, 203–203. https://doi.org/10.3389/fnhum.2013.00203