This module will cover key areas underlying the study of haematology and immunology, including the development of the blood system and stem cells, defence of the body by the innate and adaptive immune system, and the contribution of adaptive immunity in directing the immune response. We will discuss key concepts in how the immune system can combat globally-important human diseases, and what happens when an inappropriate response is mounted, for example in chronic inflammation, autoimmunity, and allergy. Fundamental links will be drawn between experimental studies, including cutting edge genetic and transcriptomic technologies, and the development of novel therapies to reflect on our continued efforts to improve human health.
Occurrence | Teaching period |
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A | Semester 2 2023-24 |
Human health and our ability as scientists to understand, treat, and cure disease has an incredible impact on communities across the globe. Underlying the development of novel drugs and therapies against pathogens, in treating autoimmunity and allergy, or in curing diseases such as cancer, is the vital research being undertaken to understand how the human host responds to and defends itself against these insults. The aim of this module is to provide a fundamental understanding of the cells, molecules, and genes involved in the immune and blood system, how these protect the host, but also how they can cause and contribute to disease. Students will explore key concepts in blood cell development, innate and adaptive immunity, and immune dysfunction, before considering how experimental work leads to novel treatments to improve human health. The module will also integrate key concepts with reference to research data, encouraging students to critically analyse primary research articles and explore new strategies in experimental design.
Students who successfully complete this module will be able to:
Understand and explain the key concepts and terminology in immune and blood cell development.
Identify the relevant cells, molecules, and genes that drive haematopoiesis, innate and adpative immunity and evaluate how this contributes to fighting human disease.
Integrate knowledge of innate and adaptive immunity to intepret the mechanisms that underlye immune disorder.
Critically assess experimental data relating to immune and blood cell function and discuss how this impacts development of novel therapies.
Explore and synthesis experimental design in the context of key haematological and immunological concepts.
Task | % of module mark |
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Online Exam -less than 24hrs (Centrally scheduled) | 100 |
None
Task | % of module mark |
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Online Exam -less than 24hrs (Centrally scheduled) | 100 |
Marks for all summative assessments will be made available to you and your supervisor via e:vision. Feedback will be either individual or cohort-level, depending on the assessment format. You should take the opportunity to discuss your marks and feedback with your supervisor.
For exam-style summative assessment, model answers will be provided for all questions along with cohort-level feedback indicating how students answered questions in general. Marks achieved per question will be added to your script.
For coursework assessments (eg. reports or essays) you will receive individual feedback on your work. This will usually be in the form of a feedback sheet that will include suggestions for further improvement.
During the teaching of the module you will receive formative feedback that may be at a whole class or individual level. Such feedback may include: model answers and discussion of workshop questions, summaries of performance in practicals, VLE-based quizzes, individual spoken comments during workshops, individual written comments on formative work.
These are available through the VLE module site.