Studying at York
Ageing & Regenerative Medicine - BIO00079H
Module summary
This module will cover the basic mechanisms underlying the ageing process and how age-related degenerative diseases emerge. A fundamental understanding of these processes has helped to stimulate the field of Regenerative Medicine; new therapies based on the use of molecules, cells and engineered tissues to effect repair and regeneration of old and worn out tissues.
Related modules
Pre-requisite modules
Co-requisite modules
- None
Prohibited combinations
- None
Module will run
| Occurrence | Teaching period |
|---|---|
| A | Autumn Term 2022-23 to Summer Term 2022-23 |
Module aims
The aims are to acquire an advanced understanding of the mechanisms underpinning cell specialisation and tissue function; to examine how dysregulation of these mechanisms as a result of ageing and environment can result in degenerative disease; to appreciate the systems level cooperation of different cellular pathways/processes for determining the outcomes of cell specialisation and pathologies; to consider how applications of molecular, cell and tissue engineering research can provide new strategies for restoration of health through regenerative medicine. This module aims to equip students with the skills to undertake a research career or other analytical career path.
Module learning outcomes
1. Explain the mechanisms underlying cellular and organismal ageing
2. Interpret the impact of ageing and environment on the development of degenerative disease and mechanisms thereof
3. Identify and explain the clinical need for regenerative medicine-based therapies and the challenges that must be overcome.
4. Evaluate with examples how cell function can be regulated by exogenous factors and cell engineering techniques.
5. Synthesise and critique a range of examples of how different cell types interact to form functional tissue structures
6. Formulate a methodological strategy using cell and tissue research techniques for chronic disease.
7. Comprehend and criticise key publications related to the field.
Indicative assessment
| Task | % of module mark |
|---|---|
| Essay/coursework | 100 |
Special assessment rules
None
Indicative reassessment
| Task | % of module mark |
|---|---|
| Essay/coursework | 100 |
Module feedback
Cohort-level feedback will be provided on performance in closed exams and made available via the VLE. Histograms of module marks will be posted on the notice boards outside the Biology Student Services office. Individual marks will be made available to you and your supervisor via e:vision. Exam scripts will be made available at the end of either the Spring or Summer terms. You should take the opportunity to discuss your marks and feedback with your supervisor.
During the teaching of the module you will receive feedback that may be at a whole class or individual level. Forms of feedback may include: model answers and discussion of workshop questions, summaries of performance in practicals, VLE-based quizzes, individual spoken comments during workshops, individual written comments on formative work.
Indicative reading
These are available through the VLE module site.