Studying at York
Genome Expression & Maintenance - BIO00051I
Module summary
This module focuses on the molecular mechanisms of DNA replication, DNA damage and repair, transcription, RNA processing and translation. Examples from both prokaryotes and eukaryotes will be used.
Module will run
| Occurrence | Teaching period |
|---|---|
| A | Autumn Term 2022-23 to Summer Term 2022-23 |
Module aims
This module focuses on the molecular mechanisms of DNA replication, DNA damage and repair, transcription, RNA processing and translation. Examples from both prokaryotes and eukaryotes will be used. Where appropriate these mechanisms are put in the context of their use in biotechnology. Students are also encouraged to participate in the post summer CAP bioinformatics teaching which aims to expose them to cutting edge bioinformatics [transcriptomics] and prepare students for possible Stage 3 projects and/or their placement year.
The module aims to provide students with the concepts and tools required to understand the dynamic molecular processes that occur in duplication, maintenance and expression of genomes. It also provides an opportunity to reinforce this understanding, and practise and extend skills learned at stage one, through application to solving problems and interpreting relevant data.
Module learning outcomes
Students who successfully complete this module will have the ability to:
1. Identify the challenges associated with genome maintenance and explain how they are overcome
2. Understand the consequences of failure of genome maintenance and how this is linked to disease and integrated with the cell cycle
3. Understand the principles and mechanisms of gene expression and its regulation
4. Undertake lab-based and bioinformatics experiments to explore and illustrate concepts in gene expression and maintenance
5. Solve problems and interpret data based on module content
6. Develop skills in independent study
Indicative assessment
| Task | % of module mark |
|---|---|
| Online Exam -less than 24hrs (Centrally scheduled) | 100 |
Special assessment rules
None
Indicative reassessment
| Task | % of module mark |
|---|---|
| Online Exam -less than 24hrs (Centrally scheduled) | 100 |
Module feedback
Cohort-level feedback will be provided on performance in closed exams and made available via the VLE. Histograms of module marks will be posted on the notice boards outside the Biology Student Services office. Individual marks will be made available to you and your supervisor via e:vision. Exam scripts will be made available at the end of either the Spring or Summer terms. You should take the opportunity to discuss your marks and feedback with your supervisor.
During the teaching of the module you will receive feedback that may be at a whole class or individual level. Forms of feedback may include: model answers and discussion of workshop questions, summaries of performance in practicals, VLE-based quizzes, individual spoken comments during workshops, individual written comments on formative work
Indicative reading
These are available through the VLE module site.