Pharmaceutical

Active Projects

BioDriveAFS – an RCT investigating the impact of a biomarker driven Antifungal Stewardship strategy on antifungal drug use and health related quality of life for patients with acute leukaemia
DISC – An RCT comparing injections of collagenase to surgical correction in the treatment of moderate Dupuytren's contracture
EXTEND – An RCT determining the effectiveness of longer antibiotic courses in improving intra-abdominal infection patient outcomes
PERISCOPE - What are the benefits and harms of continuation versus stoppage of biologics in patients with inflammatory arthritis (IA) undergoing orthopaedic surgery?
Tobacco cessation within TB programmes – An RCT assessing the effectiveness of cytisine when added to behavioural support in pulmonary TB patients smoking tobacco on a daily basis
TIDE – An RCT investigating whether there are effective alternatives to nasal mupirocin for early decolonisation of MRSA amongst adult hospital in-patients

BreatheMOR-HF – An RCT to determine whether prescribing slow-release daily morphine tablets to individuals with heart failure helps with breathlessness
HERO – Hydroxychloroquine Effectiveness in Reducing symptoms of hand Osteoarthritis: a randomised controlled trial
LEISH Sudan – A Phase IIa/IIb clinical trial to evaluate the therapeutic efficacy of ChAd63-KH vaccine in patients with persistent post kala-azar dermal leishmaniasis
PROMOTE – Placebo-controlled trial of methotrexate to treat painful knee osteoarthritis
RETREAT (F) - A feasibility study for an RCT of treatment withdrawal in psoriatic arthritis
Sleep disturbance – Pharmacological and non-pharmacological interventions for non-respiratory sleep disturbances in children with neurodevelopmental disorders: a systematic review