Trial design, analysis and reporting

Examples of YTU studies that focus on the design, analysis and reporting methods of trials are listed below:

Scantlebury AL, McDaid CM, Brealey SD, et al. Embedding qualitative research in randomised controlled trials to improve recruitment: findings from two recruitment optimisation studies of orthopaedic surgical trials. Trials 2021. Article. DOI: 10.1186/s13063-021-05420-4.

Agni N, Fairhurst CM, McDaid CM, et al. Protocol for a factorial randomised controlled trial, embedded within WHiTE 8 COPAL, of an Enhanced Trainee Principal Investigator Package and Additional Digital Nudge to increase recruitment rates. F1000research 2019. Article. DOI: 10.12688/f1000research.19743.1.

Clark L, Fairhurst C, Hewitt CE, et al. A methodological review of recent meta-analyses has found significant heterogeneity in age between randomized groups. Journal of Clinical Epidemiology 2014; 67: 1016-1024. Article. DOI: 10.1016/j.jclinepi.2014.04.007.

Hewitt CE, Kumaravel B, Dumville JC, et al. Assessing the impact of attrition in randomized controlled trials. Journal of Clinical Epidemiology 2010; 63: 1264-1270. Article. DOI: 10.1016/j.jclinepi.2010.01.010.

Hewitt CE, Gilbody SM, Mann R, et al. Instruments to identify post-natal depression: Which methods have been the most extensively validated, in what setting and in which language? International journal of psychiatry in clinical practice 2010; 14: 72-U82. Article. DOI: 10.3109/13651500903198020.

Mann R, Hewitt CE and Gilbody SM. Assessing the quality of diagnostic studies using psychometric instruments: applying QUADAS. Social psychiatry and psychiatric epidemiology 2009; 44: 300-307. Article. DOI: 10.1007/s00127-008-0440-z.