UKALL SUMMARY

UKALL 2011 investigated whether small changes to the standard treatment for acute lymphoblastic leukaemia, or ALL, and lymphoblastic lymphoma, or LBL, can reduce the side effects of the treatment and reduce the chance that the disease returns.

Lymphoblastic Lymphoma or LBL is a type of cancer. It involves the lymphatic system. This is part of your immune system. It helps to fight bacteria and other infections. The treatment for LBL is already very successful. About 8 out of 10 patients are cured of the disease. There are still two problems. First there is a risk of side effects, both during the treatment and afterwards. Second, we cannot cure all patients. We want to take the standard treatment that we currently use to treat LBL and then make a few changes.

This is to find out:

Whether we can reduce the side effects of the treatment
Whether we can reduce the chance that the disease returns.

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