Dr Puvanendran Tharmanathan
Senior Research Fellow (Associate Professor)

Profile

Biography

Puvan joined the York Trials Unit in 2010 after first training is as a Pharmacist. His post-graduate work prepared him for a broad range of functions relating to the design and conduct of clinical trials along with the synthesis of medical and health-related evidence.

Qualifications

• PhD Public Health and Epidemiology
• MSc Evidence-based medicine

Research

Overview

Puvan's research interests include interim analysis and methods used by data monitoring committees, participant-reported outcome measures and methods for evidence synthesis and meta-analysis.

Projects

• BioDrive AFS - an RCT investigating the impact of a biomarker-driven Antifungal Stewardship strategy on antifungal drug use and health-related quality of life for patients with acute leukaemia
• DISC - An RCT comparing injections of collagenase to surgical correction in the treatment of moderate Dupuytren's contracture
• EXTEND - An RCT determining the effectiveness of longer antibiotic courses in improving intra-abdominal infection patient outcomes
• PROFHER 2 - A RCT assessing the effectiveness of Reverse Shoulder Arthroplasty versus Hemiarthroplasty versus Non-surgical care for acute three and four-part fractures of the proximal humerus in older adults
• REASCENT

Completed

• HERO- Hydroxychloroquine Effectiveness in Reducing symptoms of hand Osteoarthritis
• PROMOTE- A pragmatic, double-blind, randomised, placebo-controlled trial of methotrexate to treat painful knee osteoarthritis
• YLST - Yorkshire Lung Screening Trial

Research group(s)

• Trials and Statistics

Supervision

• MSc Dissertation supervision
• PhD supervision

Publications

Full publications list

• Puvan Tharmanathan's publications

Teaching

Postgraduate

• Lecturer on Evidence-Based Practice Module (CPD Level 6)