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Laura Mandefield
Research Fellow (Statistician)

Profile

Biography

Laura joined the York Trials Unit in July 2019. She previously worked at Sheffield Clinical Trials Research Unit which she joined after completing an MSc in Statistics at the University of Leeds in 2014.

Qualifications:

  • MSc Statistics, University of Leeds
  • BSc Biological Sciences, University of Edinburgh

Research

Overview

Laura's research interests include methods for handling missing data, analysis of cluster RCTs and trials with clustering by health professional and design and analysis of diagnostic accuracy studies.

Projects

  • HAMLET - A multicentre, two-arm, non-blinded, pragmatic, parallel group, randomised controlled superiority trial assessing the clinical and cost effectiveness of Through Knee Amputation (TKA) compared to Above Knee Amputation (AKA) in patients requiring major lower limb amputations (MMLA), but who are unsuitable for a Below Knee Amputation (BKA).
  • PACT
  • PERISCOPE - What are the benefits and harms of continuation versus stoppage of biologics in patients with inflammatory arthritis (IA) undergoing orthopaedic surgery?

Previous Projects

Research group(s)

Supervision

  • Clinical trial methodology and analysis

Laura Mandefield

Contact details

Laura Mandefield
Research Fellow (Statistician)

Tel: 01904 32(1628)

@healthsciyork