Funded projects
The Centre has to date awarded £3.09 million to more than 100 new projects across eighteen departments spanning all three faculties.
We have supported an extremely broad variety of initiatives: from priming new research and running pilot projects, to seeding more translational and external-facing work, to helping establish new external partnerships. We also set up a dedicated fund for recently appointed early to mid-career researchers. Most recently we have made two final large strategic awards - read more in this news article.
Throughout the past five years, the Centre has supported interdisciplinary working across departments and faculties in order to enrich the scope and potential translatability of research.
Funded projects range from an investigation of the role of long non-coding RNA in infectious, inflammatory, and vascular diseases to a workshop to develop research proposals related to sustainable wellbeing and the UN Sustainable Development Goals, and from a review of specialist paediatric palliative care input for children with malignancies to an exploration of the benefits to individuals of a new virtual reality community singing platform.
All the projects are listed below, categorised into several broad health research areas. The titles of the individual projects link to further details about them in the York Research Database.
- Translation of Leish@York Research
- A new non-antibody scaffold for in situ detection of pathogens in wastewater
- Taking sleep research out of the laboratory
- Applying parasite genomics to understand cutaneous leishmaniasis
- The influence of inflammation activity and the role of the cerebellum in functional neurological syndromes (Conversion Disorder)
- Effects of 670nm photobiomodulation on mitochondrial function in the human brain
- Characterisation of sodium transport as a novel biomarker of aggression in colon cancer specimens
- Deep sequencing of the C9orf72 GGGGCC-repeat expansion in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
- Resurrecting ancestral sugars: a novel molecular archaeology approach to Prostate cancer immunotherapy
- Establishing a pipeline for the isolation and expansion of estrogen receptor positive (ER+) cells from healthy volunteers followed by their first characterisation using single-cell transcriptomics
- Establishing single cell RNA-sequencing and ATAC-sequencing to decipher biological heterogeneity in blood cells
- A microfluidic device for in vitro characterision of biomolecular liquid-liquid phase separation: from soft matter physics to biomedical research via solution biophysics
- Matching self-healing hydrogels to diverse cardiac tissues
- Characterisation of a molecular switch between amyotrophic lateral sclerosis and frontotemporal dementia
- Accelerating the development of new alpha therapies for cancer treatment
- Understanding how unwanted memories persist: The role of sleep spindles in emotional memory consolidation
- Infant neural and physiological responses to fear expressions as risk markers for the development of conduct disorders
- Novel methodologies and apparatus for tissue sensitive prompt gamma-ray imaging in proton therapy
- Real Time Magnetic Resonance Imaging of Swallowing and Speech in Patients Following Major Maxillofacial Surgery and Reconstruction
- Developing chaperone therapy for lysosomal storage disease treatment – Treating Mucopolysaccharidosis IIIB with imino-sugars
- Towards non coding RNA-based therapies: Developing innovative mass spectrometry methods to probe function of non-coding RNA immune regulators
- A new partnership to assess zebrafish models of human disease using evolutionary algorithms
- Investigating the relationship between sodium transport inhibitor use and clinical outcomes in cancer patients
- Characterising the role of a novel intellectual disability gene, TLK2, in neuronal development
- Understanding DNA-processing molecular motors from Human Papillomavirus for designing anti-viral drugs
- Microelectronic integrated circuit biosensors for susceptibility testing
- A new approach to stroke aphasia rehabilitation
- Investigating in a cell-free test tube how malfunction in cellular organization causes congenital glycosylation disorders
- Is human type 1 diabetes a result of immunological attack of the thymic quality control machinery?
- A feasibility study to discover if the community of microbes in our guts is affected by the way we receive antibiotics
- Building a strategic partnership between the University of York and the Barts Cancer Institute at Queen Mary University London
- microRNA markers in autism spectrum disorders
- Interpreting the electrical signals in the nervous system - towards a framework for therapeutic benefit
- Investigating the causes of changes in hearing ability using brain stimulation
- Building a Partnership for Cognitive Neuroscience between the University of York and Maastricht University
- Development of a humanised mouse model of schistosomiasis
- Artificial enzymes for selective antibiotic activation
- Chemical re-engineering of lipoteichoic acid (LTA) to decrypt its dynamic interplay with host cell surfaces
- The role of long non-coding RNA in infectious, inflammatory, and vascular diseases
- Measuring functional magnetic resonance signals in rodents
- Probing the role of ion channels in microglial activation using in vivo models
- Validation of preclinical models of ZAK-linked myopathy
- Pharmaceutical Optimisation using a Laboratory Automated Reaction Intelligent System (POLARIS)
- How do personal experiences of autism affect views of genetic research into autism?
- Does the gender achievement gap in education point toward a mental health gap? Potential pathways to narrowing gender disparities in education
- Mental Health of Children with Special Educational Needs and Disabilities during the Coronavirus Pandemic
- Tackling early childhood undernutrition and obesity in Jamaica, 1962-2018
- The origins of healthcare in its social context
- Health inequalities and the use of cannabis and cannabidiol for pain relief: a study in two deprived areas
- Workshop to develop research proposals related to sustainable wellbeing and the UN Sustainable Development Goals
- Architectures for a post-antibiotic age: the co-design of an exhibition
- Engaging with the Deaf Community: Raising awareness of the British Sign Language Translation of the Strengths and Difficulties Questionnaire
- SINGSVR: Simulating Inclusive Natural Group Singing in VR
- Digital games to tackle common mental health problems in children and young people
- How do personal experiences of autism affect views of genetic research into autism?
- Does the gender achievement gap in education point toward a mental health gap? Potential pathways to narrowing gender disparities in education
- Understanding what influences orthopedic surgical decision making: a mixed methods systematic review
- Sleep in a time of COVID-19
- Engagement workshops about inequalities in, and under-identification of, common mental disorders in the perinatal period
- Exploring the potential for Integrated Medicine approaches to improve the health and wellbeing of HIV/AIDS patients in rural Tanzania
- How can community reporters assist an understanding of experiences of food insecurity over the summer holiday amongst low-income families?
- The Closing the Gap cohort: building a platform for York-led interdisciplinary research programme in mental health
- The Umbrella Consortium – bringing together the global leaders in research into infection in children with cancer
- A feasibility study into producing a national housing profile of people with severe mental illness
- Developing methodologies to determine the fate of antibiotics and their metabolites in food crops in order to inform risk assessment for human health
- International collaboration to support English and Dutch patients with Medically Unexplained Symptoms(MUS), their carers and clinicians to independently formulate research priorities for their condition
- Implementing the Person-Centred Community Care Inventory (PERCCI) as a measure for quality in older people’s mental health and social care services
- Health inequalities and the use of cannabis and cannabidiol for pain relief: a study in two deprived areas
- Infant neural and physiological responses to fear expressions as risk markers for the development of conduct disorders
- Tobacco smoking among people living with HIV in Uganda: understanding the problem to inform effective interventions
- Polypharmacy in children and young people with life-limiting conditions: understanding the problem and identifying research priorities
- Mental Health First Aid: An intervention for improving mental health?
- A mixed methods evaluation of the impact of extending working hours in a large Mental Health Trust: assessing employee and organisational outcomes
- Developing a training intervention for staff to improve participant recruitment into randomised controlled trials
- University of York Student Wellbeing Cohort
- Addressing mental & physical health comorbidity in Low and Middle Income Countries in South Asia: establishing the York Mental and Physical Comorbidity Global Health Research Group
- Cochrane Global Mental Health: Mapping existing mental health evidence and knowledge mobilisation for people in Low and Middle Income Countries (LMICs)
- Demonstrating the Viability of Analytics for Unsupervised Healthcare Data Collection
- Improving cleft palate treatment with acoustics: Detecting Velo-Pharyngeal Insufficiency using external noise excitation
- Optimised, scaled-up production of exosomes from mesenchymal stem cells through outsourced process development
- Personalising Mental Health Treatments for Young People Using Machine Intelligence (ProMetheUs)
- A Novel Platform Technology for Synthetic Vaccines and Gene Delivery Systems
- Case studies of local NHS equity indicator trends: Have some NHS areas tackled health inequality more effectively than others, and if so how?
- Development of a Patient and Public Involvement in Research Network (PIRN) at the University of York (PIRN@York)
- Architectures for a post-antibiotic age: the co-design of an exhibition
- Implementing Outcome Feedback technology in NHS IAPT Mental Health Services
- Engaging with the Deaf Community: Raising awareness of the British Sign Language Translation of the Strengths and Difficulties Questionnaire
- TB & Tobacco PLUS: A plan to integrate and scale up tobacco cessation within TB programmes in Bangladesh and Pakistan
- SINGSVR: Simulating Inclusive Natural Group Singing in VR
- Repurposing of an approved drug for Frontotemporal Dementia
- Targeting epigenetic reader proteins to develop new drugs for Leishmaniasis
- Drug Delivery for Treatment of Neurodegenerative Diseases using Gels (NEURO-GELS)
- Digital games to tackle common mental health problems in children and young people
- Development of an automated device to monitor circadian changes in vision
- Pharmaceutical Optimisation using a Laboratory Automated Reaction Intelligent System (POLARIS)
- Specialist Paediatric Palliative Care Input for Children with Malignancies
- A Novel Framework for Enriching and Expediting Statistical and Uncertainty Analyses of Complex Computer Models of Biological Systems