Guidelines to prevent nausea and vomiting in paediatric cancer patients

Posted on 20 June 2017

The collaborative work of the Centre can make a real difference to patients and researchers, but it might take a few years to come to fruition.

In a series of papers across five years, Dr Bob Phillips worked with colleagues in Canada to produce a systematic review based series of guidelines to prevent and treat vomiting caused by chemotherapy in children undergoing cancer treatments. The papers were highlighted in a recent Editorial in the journal 'Pediatric Blood and Cancer' that lauded this work and called for more research into this aspect of cancer care.

Patel P, Robinson PD, Thackray J, Flank J, Holdsworth MT, Gibson P, Orsey A, Portwine C, Freedman J, Madden JR, Phillips R, Sung L, Dupuis LL. Guideline for the prevention of acute chemotherapy-induced nausea and vomiting in pediatric cancer patients: a focused update. Pediatr Blood Cancer 2017 Apr 28 [Epub ahead of print]

Phillips RS, Friend AJ, Gibson F, Houghton E, Gopaul S, Craig JV, Pizer B. Antiemetic medication for prevention and treatment of chemotherapy-induced nausea and vomiting in childhood. Cochrane Database Syst Rev 2016, Issue 2. Art. No.: CD007786. DOI: 10.1002/14651858.CD007786.pub3

Flank J, Robinson PD, Holdsworth M, Phillips R, Portwine C, Gibson P, Maan C, Stefin N, Sung L, Dupuis LL. Guideline for the treatment of breakthrough and the prevention of refractory chemotherapy-induced nausea and vomiting in children with cancer. Pediatr Blood Cancer 2016 Mar 9 [Epub ahead of print]

Dupuis LL, Robinson PD, Boodhan S, Holdsworth M, Portwine C, Gibson P, Phillips R, Maan C, Stefin N, Sung L; Pediatric Oncology Group of Ontario. Guideline for the prevention and treatment of anticipatory nausea and vomiting due to chemotherapy in pediatric cancer patients. Pediatr Blood Cancer 2014;61(8):1506-12