2019 to 2010
2019 2018 2017 2016 2015 2014 2013 2012 2011 2010
2019
- Merging π-Acid and Pd Catalysis: Dearomatising Spirocyclisation/ Cross Coupling Cascade Reactions of Alkyne-Tethered Aromatics.
H E Ho, M J James, T C Stephens, T C Payne, P O’Brien, R J K Taylor, W P Unsworth, ACS Catalysis, 2019, 9, 504-510.
- Indole Synthesis Using Silver Catalysis.
A K Clarke, H E Ho, J A Rossi-Ashton, R J K Taylor, W P Unsworth, Chem. - Asian J., 2019, 14, 1900 –1911.
- Synthetic and Mechanistic Studies into the Rearrangement of Spirocyclic Indolenines into Quinolones.
R G Epton, A K Clarke, R J K Taylor, J M Lynam, W P Unsworth, Eur. J. Org. Chem., 2019, 5563–5571.
- A Marine Viral Halogenase that Iodinates Diverse Substrates.
D S Gkotsi, H Ludewig, S V Sharma, J Connolly, J Dhaliwal Y Wang, W P Unsworth, R J K Taylor, M M W McLachlan, S Shanahan, J H Naismith, R J M Goss, Nature Chemistry, 2019, 11, 1091-1097.
- A Copper(II)-Mediated Radical Cross-Dehydrogenative Coupling/Sulfinic acid Elimination Approach to 2-Quinolones.
R M Gorman, T E Hurst, W F Petersen, R. J. K. Taylor, Tetrahedron, 2019, 75, 130711.
2018
- Ag(I)-Catalysed Synthesis of Azabicyclic Alkaloid Frameworks from Ketimine-tethered Ynones: Total Synthesis of Indolizidine 209D.
H E Ho, M J James, P O’Brien, R J K Taylor, W P Unsworth, Org Lett., 2018, 20, 1439-1443.
- Dearomatising Spiroannulation Reagents: Direct Access to Spirocycles from Indoles and Dihalides.
J T R Liddon, J A Rossi-Ashton, R J K Taylor, W P Unsworth, Org. Lett., 2018, 20, 3349-3353.
- Divergent Reactivity of Phenol- and Anisole-Tethered Donor-Acceptor α-Diazoketones.
A K Clarke, W P Unsworth, R J K Taylor, Tetrahedron, 2018, 74, 5374-5382.
Invited article (Barton Special Issue)
- "Back-to-Front" Indole Synthesis using Silver(I) Catalysis: Unexpected C-3 Pyrrole Activation Mode Supported by DFT.
A K Clarke, J M Lynam, R J K Taylor, W P Unsworth, ACS Catalysis, 2018, 8, 6844-6850.
- Application of Copper(II)-Mediated Radical Cross-Dehydrogenative Coupling to Prepare Spirocyclic Oxindoles and to a Formal Total Synthesis of Satavaptan.
T E Hurst, R Gorman, P Drouhin, R J K Taylor, Tetrahedron, 2018, 74, 6485-6496.
Invited article (Ghosez Special Issue)
- Divergent Reactivity of Indole-Tethered Ynones with Ag(I) and Au(I) Catalysts: A Combined Synthetic and Computational Study.
J T R Liddon, J A Rossi-Ashton, A K Clarke, J M Lynam, R J K Taylor, W P Unsworth, Synthesis, 2018, 50, 4829-4836.
2017
- Dearomatisation Approaches to Spirocyclic Dienones via the Electrophilic Activation of Alkynes.
A K Clarke, J T R Liddon, J D Cuthbertson, R J K Taylor, W P Unsworth, Org. Biomol. Chem., 2017, 15, 233-245.
- A Cu-Catalysed Radical Cross-Dehydrogenative Coupling Approach to Acridanes and Related Heterocycles.
T E Hurst, R J K Taylor, Eur. J. Org. Chem., 2017, 203-207.
- Photoredox-catalyzed reductive carbamoyl radical generation: A redox-neutral intermolecular addition–cyclization approach to functionalized 3,4-dihydroquinolin-2-ones.
W F Petersen, R J K Taylor, J R Donald, Org. Lett., 2017, 19, 874-877.
- Photoredox-Catalyzed Procedure for Carbamoyl Radical Generation: 3,4-Dihydroquinolin-2-one and Quinolin-2-one Synthesis.
W F Petersen, R J K Taylor, J R Donald, Org. Biomol. Chem., 2017, 15, 5831-5845.
- A Low-Temperature, Transition Metal-Free Cross Dehydrogenative Coupling Protocol for the Synthesis of 3,3-Disubstituted Oxindoles.
J R Donald, R J K Taylor, W F Petersen, J. Org. Chem., 2017, 82, 11288−11294.
- Selective Synthesis of Three Product Classes from Imine and Carboxylic acid Precursors via Direct Imine Acylation.
J A Rossi-Ashton, R J K Taylor, W P Unsworth, Org. Biomol. Chem., 2017, 15, 7527-7532.
2016
- Organometallic Routes to Novel Steroids Containing Heterocyclic C-17 Side-Chains.
L Vitellozzi, G D McAllister, T Genski, R J K Taylor, Synthesis 2016, 48, 48.
- A selective C–H insertion/olefination protocol for the synthesis of α-methylene-γ-butyrolactone natural products.
M G Lloyd, M D'Acunto, R J K Taylor, W P Unsworth, Org. Biomol. Chem., 2016, Advance Article
- Synthetic Studies Towards the Africanane Sesquiterpenes via the Cope Rearrangement of gem-Dimethyl Substituted Divinyl Cyclopropanes.
J D Osler, W P Unsworth, R J K Taylor, Synlett 2016, 27, 70-74.
Invited article (Steve Ley Special Issue)
- Synthesis of Spirocyclic Indolenines (Invited Review).
M J James, W P Unsworth, P O’Brien, R J K Taylor, Chem. Eur. J. 2016, 22, 2856-2881.
- From Heteroaromatic acids and Imines to Azaspirocycles: Stereoselective Synthesis and 3D Shape Analysis.
S J Chambers, G Coulthard, W P Unsworth, P O’Brien, R J K Taylor, Chem. Eur. J., 2019, 22, 6496-6500.
- Direct Imine Acylation: a Versatile Method for the Synthesis of Nitrogen Containing Heterocycles, Spirocycles and Natural Products.
W P Unsworth, R J K Taylor, Synlett, 2016, 27, 2051-2064.
- Catalyst Driven Scaffold Diversity: Divergent Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones.
J T R Liddon, M J James, A K Clarke, P O’Brien, R J K Taylor, W P Unsworth, Chem. Eur. J., 2016, 22, 8777-8780.
- Synthetic Approaches to Pallimamine and Analogues using Direct Imine Acylation.
T O Ronson, C Kitsiou, R J K Taylor, W P Unsworth, Tetrahedron, 2016, 72, 6099-6106.
Invited article (Gary Posner Special Issue)
- Selective Synthesis of Six Products from a Single Indole α-Diazocarbonyl Precursor
M J James, P O’Brien, R J K Taylor, W P Unsworth, Angew. Chem. Int. Ed., 2016, 55, 9671-9675.
- Silica-Supported Silver Nitrate as a Highly Active Dearomatising Spirocyclisation Catalyst: Synergistic Alkyne Activation by Silver Nanoparticles and Silica.
A K Clarke, M J James, P O’Brien, R J K Taylor, W P Unsworth, Angew. Chem. Int. Ed., 2016, 55, 13798-13802.
- Phosphorylated Cyclopropanes in the Synthesis of α-Alkylidene-γ-butyrolactones: Total Synthesis of (±)-Savinin, (±)-Gadain and (±)-Peperomin E.
M G Lloyd, R J K Taylor, W P Unsworth, Org. Biomol. Chem., 2016, 14, 8971-8988.
- Catalytic Dearomatization Approach to Quinolizidine Alkaloids: Five Step Total Synthesis of (±)-Lasubine II.
M J James, N Grant, P O’Brien, R J K Taylor, W P Unsworth, Org. Lett., 2016, 18, 6256-6259.
- Preparation and Reactions of Indoleninyl Halides: Versatile Scaffolds for the Synthesis of Spirocyclic Indole Derivatives.
J T R Liddon, A K Clarke, R J K Taylor, W P Unsworth, Org. Lett., 2016, 18, 6328-6333.
2015
- Total Synthesis and Stereochemical Revision of Phacelocarpus 2-Pyrone A.
T O Ronson, M Burns, M H H Voelkel, K Evans, J M Lynam, R J K Taylor, I J S Fairlamb, Chem: Eur, J., 2015, online.
- Silver(I)-Catalyzed Dearomatization of Alkyne-Tethered Indoles: Divergent Synthesis of Spirocyclic Indolenines and Carbazoles.
M J James, R E Clubley, K Y Palate, T J Procter, A C Wyton, P O'Brien, R J K Taylor, W P Unsworth, Org. Lett., 2015, 17, 4372.
- Synthetic Studies towards the Africanane Sesquiterpenes via the Cope Rearrangement of gem-Dimethyl-Substituted Divinyl Cyclopropanes.
J D Osler, W P Unsworth, R J K Taylor, Synlett, 26, online.
- Silver(I)- or Copper(II)-Mediated Dearomatization of Aromatic Ynones: Direct Access to Spirocyclic Scaffolds.
M J James, J D Cuthbertson, P A O'Brien, R J K Taylor, W. P. Unsworth, Angew. Chemie Int. Ed., 2015, 54, 7640.
- α-Alkylidene-γ-butyrolactone synthesis via one-pot C–H insertion/olefination: substrate scope and the total synthesis of (±)-cedarmycins A and B.
M G Lloyd, M D'Acunto, R J K Taylor, W P Unsworth, Tetrahedron, 2015, 71, 7107.
- Substrate scope in the copper-mediated construction of bis-oxindoles via a double C-H/Ar-H coupling process.
P Drouhin, T E Hurst, A C Whitwood, R J K Taylor, Tetrahedron, 2015, 71, 7124.
- The total synthesis of (+)-elaeokanidine A: natural product or isolation artefact?
J D Cuthbertson, W P Unsworth, C L Moody, R J K Taylor, Tetrahedron Lett., 2015, 56, 3123.
- Propylphosphonic anhydride (T3P) mediated synthesis of β-lactams from imines and aryl-substituted acetic acids.
G Coulthard, W P Unsworth, R J K Taylor, Tetrahedron Lett., 2015, 56, 3113.
- Macrocyclic polyenynes: A stereoselective route to vinyl-ether-containing skipped diene systems.
T O Ronson, M H H Voelkel, R J K Taylor, I J S Fairlamb, Chem. Commun., 2015, 51, 8034.
- A copper-mediated oxidative coupling route to 3H- and 1H-indoles from N-aryl-enamines.
P Drouhin, R J K Taylor, Eur. J. Org. Chem., 2015, 2333.
- AsCat and FurCat: new Pd catalysts for selective room-temperature Stille cross-couplings of benzyl chlorides with organostannanes.
T O Ronson, J R Carney, A C Whitwood, R J K Taylor, I J S Fairlamb, Chem. Commun., 2015, 51, 3466.
- Palladium-catalysed macrocyclisations in the total synthesis of natural products.
T O Ronson, R J K Taylor, I J S Fairlamb, Tetrahedron, 2015, 71, 989.
- Special Memorial Issue for Professor Alan Katritzky.
R J K Taylor, Tetrahedron, 2015, 71, 7101.
2014
- A Direct C-H/Ar-H Coupling Approach to Oxindoles, Thio-oxindoles, 3,4-Dihydro-1 H-quinolin-2-ones, and 1,2,3,4-Tetrahydroquinolines.
T E Hurst, R M Gorman, P Drouhin, A Perry, and R J K Taylor, Chem. Eur. J., 2014, 20, 14063.
- 4-Hydroxy-6-alkyl-2-pyrones as nucleophilic coupling partners in Mitsunobu reactions and oxa-Michael additions.
M J Burns, T O Ronson, R J K Taylor and I J S Fairlamb, Beilstein J. Org. Chem., 2014, 10, 1159.
- Copper-Mediated Construction of Spirocyclic Bis-oxindoles via a Double C–H, Ar–H Coupling Process.
P Drouhin, T E Hurst, A C Whitwood, and R J K Taylor, Org. Lett., 2014, 16, 4900.
- Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives: the total synthesis (±)-cavidine.
C Kitsiou, W P Unsworth, G Coulthard, and R J K Taylor, Tetrahedron, 2014, 70, 7172.
- A One-Pot C–H Insertion/Olefination Sequence for the Formation of α-Alkylidene-γ-butyrolactones.
M G Lloyd, R J K Taylor and W P Unsworth, Org. Lett., 2014, 16, 2772.
- Direct Imine Acylation for Molecular Diversity in Heterocyclic Synthesis.
W P Unsworth, G Coulthard, C Kitsiou, and R J K Taylor, J. Org. Chem., 2014, 79, 1368.
2013
- The Cope rearrangement of gem-dimethyl substituted divinylcyclopropanes.
J D Osler, W P Unsworth and R J K Taylor, Org. Biomol. Chem., 2013, 11, 7587.
- ‘Upenamide: trials and tribulations.
W P Unsworth and R J K Taylor, Org. Biomol. Chem., 2013, 11, 7250.
- Total Synthesis of Spirobacillene A.
W P Unsworth, J D Cuthbertson and R J K Taylor, Org. Lett., 2013, 15, 3306.
- An Expedient Protecting-Group-Free Total Synthesis of (±)-Dievodiamine.
W P Unsworth, C Kitsiou and R J K Taylor, Org. Lett., 2013, 15, 3302.
- Stereocontrolled Synthesis of the AB Rings of Samaderine C.
D J Burns, S Mommer, P A O’Brien, R J K Taylor, A C Whitwood and S Hachisu, Org. Lett., 2013, 15, 394.
- Stereocontrolled Routes to 4-Methoxypentadienoates for Use in Natural Product Synthesis.
P G E Craven and R J K Taylor, Synlett, 2013, 24, 363.
- Direct Imine Acylation: Synthesis of the Proposed Structures of ‘Upenamide.
W P Unsworth, K A Gallagher, M l Jean, J P Schmidt, L J Diorazio and R J K Taylor, Org. Lett., 2013, 15, 262.
- Direct Imine Acylation: Rapid Access to Diverse Heterocyclic Scaffolds.
W P Unsworth, C Kitsiou and R J K Taylor, Org. Lett., 2013, 15, 258.
- A Telescoped Route to 2,6-Disubstituted 2,3,4,5-Tetrahydropyridines and 2,6-syn-Disubstituted Piperidines: Total Synthesis of (−)-Grandisine G.
J D Cuthbertson and R J K Taylor, Angew. Chemie Int. Ed., 2013, 52, 1490.
2012
- Catalytic asymmetric synthesis of butane diacetal-protected (4S,5S)-dihydroxycyclohexen-1-one and use in natural product synthesis.
D J Burns, Si Hachisu, P O'Brien and R J K Taylor, Org. Biomol. Chem., 2012, 10, 7666.
- Total synthesis and structural confirmation of (±)-cuevaene A.
P G E Craven and R J K Taylor, Tetrahedron Lett., 2012, 53, 5422.
- Preparation of 3-Alkylated Oxindoles from N-Benzyl Aniline via a Cu(II)-Mediated Anilide Cyclization Process.
D S Pugh, R J K Taylor, J S Alford and H M L Davies, Org. Synth., 2012, 89, 438.
- An expedient synthesis of the proposed biosynthetic precursor of the oxepine natural product, janoxepin.
R G Doveston and R J K Taylor, Tetrahedron Lett., 2012, 53, 2533.
- Total Synthesis of an Oxepine Natural Product, (±)-Janoxepin.
R G Doveston, R Steendam, S Jones and R J K Taylor, Org. Lett., 2012, 14, 1122.
- Copper-catalysed approach to spirocyclic oxindoles via a direct C–H, Ar-H functionalisation.
C L Moody, V Franckevicious, P Drouhin, J E M N Klein and R J K Taylor, Tetrahedron Lett., 2012, 53, 1897.
- Alkyne-Acetal Cyclisation Reactions Mediated by Formic Acid; 3-Acylated-2,5-dihydrofurans and Related Oxygen and Nitrogen Heterocycles.
J Cuthbertson, A Godfrey, W P Unsworth and R J K Taylor, Heterocycles, 2012, 84, 1013.
2011
- Formal synthesis of (+)-neooxazolomycin via a Stille cross-coupling/deconjugation route.
R Bastin, J W Dale, M G Edwards, J P N Papillon, M R Webb and R J K Taylor, Tetrahedron, 2011, 51, 10026.
- Transition-Metal-Mediated Routes to 3,3-Disubstituted Oxindoles through Anilide Cyclisation.
J E M N Klein and R J K Taylor, Eur. J. Org. Chem., 2011, 6821.
- Asymmetric Decarboxylative Allylation of Oxindoles.
V Franckevicius, J D Cuthbertson, M Pickworth, D S Pugh and R J K Taylor, Org. Lett., 2011, 13, 4264.
- The Preparation of (−)-Grandisine B from (+)-Grandisine D; A Biomimetic Total Synthesis or Formation of an Isolation Artefact?
J Cuthbertson, A Godfrey and R J K Taylor, Org. Lett., 2011, 13, 3976.
- Synthesis of isoquinuclidinones via a tandem amination/imination sequence: application to the synthesis of (−)-mearsine
J Cuthbertson, A Godfrey and R J K Taylor, Tetrahedron Lett., 2011, 52, 2024.
- A one pot oxidation / allylation / oxidation sequence for the preparation of β,γ-unsaturated ketones directly from primary alcohols.
C L Moody, D S Pugh and R J K Taylor, Tetrahedron Lett., 2011, 52, 2511.
- Tetra-[μ]2-acetato-diacetatodi-[μ]3-hydroxido-tetrakis[piperidinecopper(II)] dihydrate.
J E M N Klein, R J Thatcher, A C Whitwood and R J K Taylor, Acta Cryst. C, 2011, 67, m108-m110.
- Synthesis of yomogin using a telescoped α-methylene- γ-butyrolactone annelation procedure.
R Kitson, G McAllister and R J K Taylor, Tetrahedron Lett., 2011, 52, 561.
- The First Syntheses of (±)-SDEF 678 Metabolite and (±)-Speciosins A–C.
D R Hookins, A R Burns and R J K Taylor, Eur. J. Org. Chem., 2011, 451.
- Synthetic Approaches to Enantiomerically Enriched 4-Hydroxycyclohex-2-en-1-one - A Key Chiral Building Block in Complex Natural Product Synthesis.
A R Burns and R J K Taylor, Synthesis, 2011, 681.
2010
- A double oxidation procedure for the preparation of halogen-substituted para-benzoquinone monoketals: Asymmetric synthesis of (-)-harveynone.
D R Hookins and R J K Taylor, Tetrahedron Lett., 2010, 51, 6619.
- A Tandem Amination/Lactamisation Route to 2-Azabicyclo[2.2.2]octanones.
J D Cuthbertson, A A Godfrey and R J K Taylor, Synlett, 2010, 2805.
- Pd-catalysed regioselective C–H functionalisation of 2-pyrones.
M J Burns, R J Thatcher, R J K Taylor and I J S Fairlamb, Dalton Trans., 2010, 10391.
- Highly regio- and chemoselective palladium(0)-mediated allylic substitution of difunctional allylic halides with phenols.
A R Kapdi, R J K Taylor and I J S Fairlamb, Tetrahedron Lett., 2010, 51, 6378.
- First C−H Activation Route to Oxindoles using Copper Catalysis.
J E M N Klein, A Perry, D S Pugh and R J K Taylor, Org. Lett., 2010, 12, 3446.
- 3-Alkenyl-oxindoles: Natural Products, Pharmaceuticals, and Recent Synthetic Advances in Tandem/Telescoped Approaches.
A Millemaggi and R J K Taylor, Eur. J. Org. Chem., 2010, 4527 (front cover).
- Total Synthesis and Structural Reassignment of (+)-Dictyosphaeric Acid A: A Tandem Intramolecular Michael Addition/Alkene Migration Approach.
A R Burns, G D McAllister, S E Shanahan and R J K Taylor, Angew. Chemie Int. Ed., 2010, 49, 5574.
- Recent Advances in the Chemistry of 1,2,4-Triazines.
S A Raw and R J K Taylor in "Advances in Heterocyclic Chemistry", ed A R Katritzky, Elsevier, Oxford, 2010, 75-100.
- Tandem Horner-Wadsworth-Emmons Heck procedures for the preparation of 3-alkenyl-oxindoles: The synthesis of semaxanib and GW441756.
J Lubkoll, A Millemaggi, A Perry and R J K Talyor, Tetrahedron, 2010, 66, 6606.
- Preparation of 3-Alkyl-Oxindoles by Copper(II)-Mediated C-H, Ar-H Coupling Followed by Decarboxyalkylation.
D S Pugh, J E M N Klein, A Perry and R J K Taylor, Synlett, 2010, 934-938.
- The Emergence of Palladium(IV) Chemistry in Synthesis and Catalysis.
I J S Fairlamb, P Sehnal and R J K Taylor, Chem. Rev. 2010, 110, 824-889.
- The Preparation of Substituted Pyrazoles from β,β-Dibromo-enones by a Tandem Condensation/Suzuki-Miyaura Cross-Coupling Process.
S Beltrán-Rodil, M G Edwards, D S Pugh, M Reid and R J K Taylor, Synlett, 2010, 602-606.