2023-24 events
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Ubiquitin modulators of immune signalling
Professor Benedikt Kessler (University of Oxford) presents his work on ubiquitin and protease biology. Hosted by Dr Adam Dowle.
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ONLINE: The biology of parasite sex
This week we welcome Professor Boris Striepen (University of Pennsylvania) as our first International Online seminar speaker.
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Metabolomics approaches to understand how trypanosomatids resist drugs and the immune system
Professor Michael Barrett (University of Glasgow) presents his work on how drugs work against parasites and how parasites become resistant to drugs. Hosted by Dr Samadhan Patil.
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Visualisation of human telomeric complexes by cryo-EM
Dr Kelly Nguyen (MRC Laboratory of Molecular Biology) presents her work on using structural biology to investigate telomere biology, ultimately used for therapeutic studies targeting cancers and ageing
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Dissecting human haematopoietic stem cell function at single cell resolution
Professor Elisa Laurenti (University of Cambridge) presents her work on investigating how cell cycle regulation, inflammation & ageing affect human haematopoietic stem cells unique molecular and functional properties. Hosted by Professor Dave Kent.
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Investigating clonal dynamics and effects of environmental factors in clonal haematopoiesis
Dr Kasper Rasmussen presents his work on dissecting the mechanisms by which the proteins regulating the DNA methylation landscape affects chromatin structure and gene expression patterns in hematopoietic cells. Hosted by Professor Dave Kent.
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Macrophages, Matrix & Metazoan Parasites
Professor Judi Allen (University of Manchester) shares her work on investigating the function of macrophages activated by type 2 cytokines and their role in anti-helminth immunity. Hosted by Dr Cécile Crosnier.
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Investigating chromatin complexes: evolutional conservation and understanding chromatin’s role in DNA methylation
Dr Marcus Wilson (University of Edinburgh) presents his work on understanding how epigenetic marks are placed, read and interpreted on chromatin using single-particle cryo-electron microscopy (cryo-EM). Hosted by Dr Nathaniel Jones.
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Targeting the NLRP3 inflammasome for the treatment of inflammatory diseases
Dr Rebecca Coll (Queens University Belfast) presents her work on innate immunity in humans and the development of inhibitors against a range of inflammatory conditions. Hosted by Dr Dave Boucher.
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Design and Synthesis of Bioactive Peptides and Peptoids
Professor Steven Cobb presents his work on Peptide Drug Design and Delivery, Peptidomimetics and Bioorganic Fluorine Chemistry. Hosted by Dr Chris Spicer.
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Identifying new regulators of ILC2s and type-2 immune-mediated inflammation
Dr Andrew McKenzie (MRC Lab Molecular Biology) presents his work on how the innate immune system and adaptive immune system protect the body from infection, but can also lead to inflammation and pathology. Hosted by Dr Jillian Barlow.
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POSTPONED: How PROTAC degraders work: Molecular recognition and design principles
Professor Alessio Ciulli (University of Dundee) presents his work on protein-protein interactions and protein degradation to discover novel therapeutics. Hosted by Dr Bill Grey.
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Reassessing red blood cell invasion in malaria parasites
Dr Rob Moon (London School of Hygiene & Tropical Medicine) presents his work on malaria, addressing mechanisms by which the parasites move into and invade host cells and tissues in both mosquito and human hosts. Hosted by Professor Gavin Wright.
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Mapping dynamic re-localization of the subcellular transcriptome and proteome
Professor Kathryn Lilley (University of Cambridge) shares her work on the development of cutting edge proteomics technologies. Hosted by Professor Gavin Thomas.
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Rapid expansion and diversification of an exported effector kinase family in pathogenic Malaria causing parasites
Dr Moritz Treeck (Gulbenkian Institute, IGC) presents his work on host- pathogen interactions with the parasites Plasmodium falciparum and Toxoplasma gondii. Hosted by Dr Joana Faria.
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Decoding Ductal Carcinoma in Situ (DCIS) Progression via Digital Pathology, AI-Based Analysis, and 3D Cell Modelling
Dr Nina Moderau (Imperial College London) presents her work on a multi-gene 3D breast cancer model. Hosted by Dr Andy Holding.
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Astrocyte contributions to clearing tau aggregates in Alzheimer's disease and other tauopathies
Professor Wendy Noble (University of Exeter) presents her work on understanding the molecular mechanisms underlying neurodegenerative diseases. Hosted by Dr Ines Hahn.
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Switching, Counting and Amplifying: Addressing challenges of point-of-care biosensors
Professor Christoph Wälti presents his work on molecular nanotechnology, with particular focus on the challenges of point-of-care biosensors. Hosted by Professor Steven Johnson.
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Genomics workshop
For a special edition of the Friday BMS seminars, we are running a Genomics workshop kindly sponsored by BGI. Hosted by Dr Joana Faria.
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The kinetic-segregation model of T-cell receptor triggering
Professor Simon Davis (University of Oxford) presents his work on the kinetic-segregation model of T-cell receptor triggering. Hosted by Professor Gavin Wright.
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How arsenic cures Acute Promyelocytic Leukaemia
Professor Ron Hay (University of Dundee) presents his work on how arsenic cures Acute Promyelocytic Leukaemia. Hosted by Dr Joana Faria.
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Microbial microproteins as mediators of microbe-microbe and microbe-host communication and warfare
Dr Ami Bhatt (Stanford University) showcases her work on understanding the impact (positive and negative) of the microbiome on immunocompromised patient outcomes. Hosted by Professor Adele Fielding.
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Using functional anatomical models of Naming, Reading and Speech to increase our understanding of recovery from aphasia after stroke
Professor Cathy Price (UCL) presents her work on how the brain supports language processing - including speech processing, reading and object naming in the neurotypical brain and language recovery after stroke. Hosted by Professor Beth Jefferies.
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Antimicrobial resistance in the human gut microbiome
Professor Willem van Schaik (University of Birmingham) introduces his work on characterization of the mechanisms by which commensal bacteria evolve to become multi-drug resistant opportunistic pathogens. Hosted by Professor Marjan van der Woude.
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Chemical fragments (and a little cryo EM) for drug discovery
Professor Martin Noble (Newcastle University) introduces his work on chemical fragments for drug discovery. Hosted by Dr Jamie Blaza.
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POSTPONED
POSTPONED