Perspectives on cancer subtypes - From genomics to molecular pathology

Seminar
  • Date and time: Friday 26 July 2019, 12pm
  • Location: Dianna Bowles Lecture Theatre (B/K/018)
  • Booking:

Event details

About ten years ago, high throughput molecular techniques started to be used to classify tumors of the urinary bladder. Researchers from Lund, Sweden, were the first to publish a comprehensive taxonomy of bladder cancer subtypes based on transriptomics.

A decade later, consensus has been reached among research groups worldwide on a unified molecular subtype classification system. In this lecture, Gottfrid Sjödahl, a basic pre-clinical cancer researcher at the Department of Urology at Lund University, will present how 10 years of molecular subtyping has provided a completely new framework for understanding bladder cancer biology. An insider's perspective will be given on the effort to reconcile RNA-based subtypes with established molecular pathology.

Finally, a direction for the future will be presented along with results from ongoing projects, including longitudinal subtyping during bladder cancer progression and how prospective RNA-seq is implemented in real-time to patients operated in the south of Sweden.

Dr Gottfrid Sjödahl

Lund University, Sweden