Despite being small, CBR at York leads an internationally recognised fundamental and applied clinical research portfolio. 

Since 2017 we've attracted almost £22m in active research funding (MRC, NIHR, CRUK, Gates Foundation, Blood Cancer UK and industrial partnerships) and publish in leading journals (Science, Nature, Cell Stem Cell, Science Translational Medicine, Cancer Discovery, Blood, Nature Communications and Lancet Haematology). 

CBR at York has a number of industrial collaborations some of which have led to Phase I clinical trials (INCA033989 monoclonal antibody - Incyte), we produce evidence that impacts on NICE (National Institute for Health and Care Excellence) treatment guidelines for haematological malignancies (leukaemia, lymphoma and myeloma) and run national clinical trials in haematology (eg UKALL15, FLAIR). 

Research Impact

CBR at York has an ambitious vision to catapult Yorkshire and the Humber to the forefront of blood research through:

  • policy making and clinical guidance
  • high-impact publications
  • development of biologics and technologies
  • patient and public Involvement (PPI)
  • engagement with industry
  • clinical training.

Our key objective is to contribute to society and to cultivate future talent through strategic and sustainable expansion.

Contact us

Centre for Blood Research

cbr-enquiries@york.ac.uk
@CBR_UoY

Recent publications 

Take a look at our publications list, which brings together a wide breadth of relevant outputs.

 

    Peer-reviewed journal articles 
Authors  Year Title 
   

2023

Stevens, W.B.C. ... et al. 2023

Genetic and microenvironment features do not distinguish follicular lymphoma patients requiring immediate or deferred treatment

     
Kasamba, I. ... et al. 2023 Thirty years of change in HIV incidence among adults in the Kyamulibwa General Population Cohort in rural southwest Uganda, 1989-2021
     
Motlhale, M. ... et al. 2023 Kaposi sarcoma-associated herpesvirus, HIV-1 and Kaposi sarcoma risk in black South Africans diagnosed with cancer during antiretroviral treatment rollout
     
Porteous, A. ... et al. 2023 An economic model to establish the costs associated with routes to presentation for patients with multiple myeloma in the UK
     
Mugisha, J. ... et al. 2023 SARS-CoV-2 Omicron BA.5 infections in vaccinated persons, rural Uganda
     
Sengayi-Muchengeti, M., ... et al. 2023 Thirteen cancers associated with HIV infection in a black South African cancer patient population (1995-2016)
   

 

Singini, M. G., ... et al. 2023 Usefulness of high-risk HPV early oncoprotein (E6 and E7) serological markers in the detection of cervical cancer: A systematic review and meta-analysis
   

2022  

Efficace, Fabio 2022 Raising the standards of patient-centered outcomes research in myelodysplastic syndromes: Clinical utility and validation of the subscales of the QUALMS from the MDS-RIGHT project
     
Madry, Krzysztof 2022 Cause of death and excess mortality in patients with lower-risk myelodysplastic syndromes (MDS): a report from the European MDS registry
     
Bewicke-Copley, Findlay, ... et al. 2022

Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type Diffuse Large B Cell Lymphoma

     
Fabian, J., ... et al. 2022

Measurement of kidney function in Malawi, South Africa, and Uganda: a multicohort study

     

Vries, G.T.L., ... et al.

2022

Genomic and microenvironmental landscape of stage I follicular lymphoma, compared to stage III/IV

     

Fatumo, S. ... et al.

2022

Uganda Genome Resource: A rich research database for genomic studies of communicable and non-communicable diseases in Africa 

     

Tirtakusuma, R.,  ... et al.

2022

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukaemia

     

Motlhale, M., ... et al.

2022

Lifestyle factors associated with sex differences in Kaposi sarcoma incidence among adult black South Africans

     

Schraw, J., ... et al. 

2022

Infant feeding practices and childhood acute leukemia: findings from the Childhood Cancer & Leukemia International Consortium:

     
Wang, S.S., ... et al.   2022

B-Cell NHL Subtype Risk Associated with Autoimmune Conditions and PRS

     
Crouch, S., ... et al.  2022

Molecular subclusters of follicular lymphoma : a report from the UK's Haematological Malignancy Research Network

     
Sabourin, K. R., ... et al.  2022

Environmental determinants of Kaposi's sarcoma-associated herpesvirus (KSHV) transmission in rural Uganda (ENDKU study): Contributions to research on KSHV infection and reactivation in African children: A longitudinal cohort study

     
Kalyesubula, R., ... et al.  2022

Association of impaired kidney function with mortality in rural Uganda: results of a general population cohort study

     
Motlhale, M., ... et al. 2022

Epidemiology of Kaposi’s sarcoma in sub-Saharan Africa

     
McCaughen, D.,  ... et al.  2022

Treatment decision making (TDM): A qualitative study exploring the perspectives of patients with chronic haematological cancers 

     
Singini, M. G., ... et al. 2022

HPV types 16/18 L1 E6 and E7 proteins seropositivity and cervical cancer risk in HIV-positive and HIV-negative black South African women

     
Kane, E., ... et al. 2022

Excess morbidity and mortality among survivors of childhood acute lymphoblastic leukaemia: 25 years of follow-up from the United Kingdom Childhood Cancer Study (UKCCS) population-based matched cohort

     
Howell, D., ... et al.   2022

Incurable but treatable: Understanding, uncertainty and impact in chronic blood cancers: A qualitative study from the UK's Haematological Malignancy Research Network

     

Roman, E., ... et al.

2022

Cohort Profile Update: The Haematological Malignancy Research Network (HMRN) UK population-based cohorts

   

2021

Wouters, H.J.C.M., … et al. 2021

The anemia-independent impact of myelodysplastic syndromes on health-related quality of life

     
Nalwoga, A. … et al 2021 Kaposi’s sarcoma-associated herpesvirus T cell responses in HIV seronegative individuals from rural Uganda
     
Singini, M. G. … et al.  2021 Ranking lifestyle risk factors for cervical cancer among black women: A case-control study from Johannesburg, South Africa 
     
Namale, G. … et al.   2021

HIV sero-positivity and risk factors for ischaemic and haemorrhagic stroke in hospitalised patients in Uganda: A prospective-case-control study

     
Chun Gong … et al.  2021

Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis

     
Kansiime, S., … et al. 2021

Blood pressure levels among children in rural Uganda: results from 1913 children in a general population survey

     
Oster, H. S., … et al.   2021

A predictive algorithm using clinical and laboratory parameters may assist in ruling out and in diagnosing MDS

     
Joseph John, M. … et al. 2021

The long shadow of socioeconomic deprivation over the modern management of acute myeloid leukemia: time to unravel the challenges

     
Fatumo, S., … et al. 2021

Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans

     
Risher, K. A., … et al. 2021

Age patterns of HIV incidence in eastern and southern Africa: a modelling analysis of observational population-based cohort studies

     
Bukenya, D. … et al. 2021

Stroke survivors' knowledge of risk factors for stroke and their post-stroke care seeking experiences: a cross-sectional study in rural southwestern Uganda.

     
Richards, S. J., … et al.  2021 

The incidence and prevalence of patients with paroxysmal nocturnal haemoglobinuria and aplastic anaemia PNH syndrome: A retrospective analysis of the UK’s population-based haematological malignancy research network 2004-2018

     
Hoeks, M., … et al.   2021 

Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome  

     
Martinez-Calle, N., … et al.   2021 

Systemic ALCL Treated in Routine Clinical Practice: Outcomes Following First-Line Chemotherapy from a Multicentre Cohort   

     
Greiner, R., … et al. 2021

Associations between low HDL, sex and cardiovascular risk markers are substantially different in sub-Saharan Africa and the UK: analysis of four population studies 

     
Watts, D. P., … et al.  2021  Photon quantum entanglement in the MeV regime and its application in PET imaging 
     
Namale, G., … et al. 2021

Visual inspection with acetic acid (VIA) positivity among female sex workers: a cross-sectional study highlighting one-year experiences in early detection of pre-cancerous and cancerous cervical lesions in Kampala, Uganda 

     
Waddell, K., … et al.   2021  A ten-year study of Retinoblastoma in Uganda: An approach to improving outcome with limited resources
     
Arisue, N., … et al. 2021

Assessment of mixed plasmodium falciparum sera5 infection in endemic Burkitt lymphoma: A case-control study in Malawi

     
Johnston, W. T., … et al.    2021  Childhood cancer: estimating regional and global incidence
     
Sallah, N., … et al.  2021 

Antibody response patterns to Helicobacter pylori infection in a rural Ugandan population cohort

     
Lamb, M. J. E., … et al.  2021

Health impact of monoclonal gammopathy of undetermined significance (MGUS) and monoclonal B-cell lymphocytosis (MBL): findings from a UK population-based cohort

     
Watad, A., … et al.  2021

Somatic mutations and the risk of undifferentiated autoinflammatory disease in MDS: an under-recognized but prognostically important complication

     
Sheridan, R. … et al. 2021 Preferred and actual place of death in haematological malignancies: a report from the UK haematological malignancy research network 
     

Contact us

Centre for Blood Research

cbr-enquiries@york.ac.uk
@CBR_UoY