PhD thesis research topics within the scope of the programme will be identified and developed by the student at the end of the Foundation year in collaboration with academics drawn from the programme supervisory pool (please see training tab).An indicative list of interdisciplinary researchers associated with the programme and available as prospective members of the PhD supervisory team are provided below.
Name |
Department/ Centre Affiliation |
Research Area |
Protein-nucleic acid interactions; X-ray crystallography |
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DNA/protein interactions, plasmid segregation; multidrug resistance |
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Single molecule techniques, molecular motors, microbiology |
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six main research areas, mostly in aspects of mathematical biology, fluid dynamics and/or pattern formation: | ||
Host-pathogen coevolution, within-host evolution, antibiotic resistance | ||
Structural biology, membrane proteins; method development |
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Simulation of complex biosystems; tools for data analysis/visualization |
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Developmental immunology; haematopoesis/stroma; 4D imaging |
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Machine learning; inductive logic programming |
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Structural Biology / cellular roles for carbohydrates / |
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NMR, sensitive screening methods |
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Metal ions in biology and medicine |
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Catalysis: reactivity, mechanism and application (chemical biology and target-orientated synthesis) |
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Chemical glycobiology, synthetic carbohydrate chemistry, chemical/enzymatic modification of proteins | ||
Computational models: predator prey; network analysis |
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Targeted metabolomics for drug development |
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Immunology; auotimmune disease; diabetes |
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Hancock. Yvette |
Theoretical modelling of nanocarbon for biological application, and Raman spectroscopy of biological systems |
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Structure based ligand discovery |
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Research within the Biomolecular Electronics Group is focussed on the integration, detection and manipulation of biological materials, such as DNA, peptides and proteins, with nanoelectronic devices |
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Immune regulation; experimental leishmaniasis |
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Immunology, immune regulation of intestinal inflammation | ||
Phase 1 clinical trials of vaccines and microbicides against HIV; also research on HPV, Chlamydia and Leishmania | ||
MicroRNA biology; Host-pathogen interactions; Endothelial cell biology | ||
Research specializes on the theme of Single-molecule cellular biophysics. |
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Prevention of mother to child transmission of HIV and the natural history and management of HTLV-1 associated myelopathy in the UK. Also investigates operational, translational and clinical research as well as multidisciplinary team management. | ||
DNA replication, recombination and repair. Molecular motors. Genetic disease. | ||
Structure/function of papilloma virus; prostate cancer |
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Bacterial pathogenesis; antimicrobial strategies |
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Low temperature plasmas and their technological applications | ||
Bacterial activation of small molecules / redox metalloenzyme |
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Stochastic modeling of uncertainty & dynamics in biological systems |
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Protein/protein and protein/nucleic acid interactions; Structural Biology; NMR spectroscopy | ||
Engineering simulations for research into complex systems | ||
Structural biology, NMR spectroscopy; host pathogen interactions |
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Intracellular pathogen survival mechanisms; cell biology |
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Combinatorial/high throughput synthesis; antimicrobials |
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Chemokine receptor function and regulation |
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Nanochemistry, nanomedicine, nanomaterials, gene therapy |
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Discovery of novel antibiotics. Antibiotic resistance |
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Human epithelium; tissue development |
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Simulation of complex biosystems, computational modeling |
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Compound synthesis |
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Structure /function of bacterial transporters; systems biology, bioinformatics |
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Biological mass spectrometry; host-microbe interactions |
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Artificial immune systems, modeling complex systems |
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Novel analytical/computational tools; modeling virus structure/assembly |
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Microbial pathogenesis/ gene regulation, biofilms |
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Plasma physics; modelling medical plasmas and interactions with biofilms |
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Regulators of Leishmania spp. parasite differentiation that enable human leukocyte infection, with emphasis on post-transcriptional control as the primary mode of gene regulation |
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Compound synthesis, bioinorganic chemisitry |
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Protein structure/function & crystallography |
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Chemoinformatics; novel pattern recognition techniques; metabolomics |
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Theoretical and simulation tools, biological models |